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: Lower back pain is universally common issue. It can be experienced at any age, and most people experience at least once in their life. Low back pain (LBP) describes pain between the lower edge of the ribs and the buttock. The first episode usually occurs between early years of age. Nurses are vulnerable and ignored so they must supposed to be knowledgeable about the risk factors and preventive measures and effectively apply it into practice to prevent them from sustaining back injuries. Pain often gets better with rest, physical therapy and medication. Reduce your risk of low back pain by keeping at a healthy weight and staying active. Hence different treatments are available for it but knowledge and primary prevention is essential as core for any. This study done on a total of 50 second year B.Sc nursing students were selected in a college The study reveals that the structured teaching programme could increase the knowledge level of student nurse and it should be an on-going process. The findings of the present study have implications for Nursing practice like clinical instructor should expertise in assisting the student nurses to improve the knowledge about preventive measures of low back pain